The aim of this study was to assess the relative cost-effectiveness of escitalopram compared with citalopram in patients with major depressive disorder.
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Nglish physician who pioneered the development of neurology as a medical specialty during the reign of Queen Victoria. Jackson first became interested in neurology when he became a staff member of the National Hospital Queen Square. There began his first stimulation in the study of seizures. He gained importance, not only based on his description of a certain seizure pattern "Jacksonian Epilepsy, " but on his formulation of concepts, even principles, that explain paroxysmal seizures of all types. John Hughlings Jackson has been called the "father of English neurology." Jackson made a number of scientific discoveries in several areas of higher nervous activity and language, and contributed greatly to the study of various types of epilepsy, for instance, escitalopram oral.
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Lifeline is published monthly by the American College of Emergency Physicians State Chapter of California, Inc. 1020 - 11th Street, Suite 310 Sacramento, CA 95814 916 ; 325-5455 Phone 916 ; 325-5459 Fax E-mail: calacep calacep Web site: calacep 1-800-735-ACEP 2237 ; 2002 American College of Emergency Physicians State Chapter of California, Inc. Medical Co-Editors Gene Hern, MD & Dustin Smith, MD Senior Editor Terrie Page, Executive Director Associate Editor Deanna M. Janey Director of Administrative Services, for example, escitalopram 10mg.
Lf you want to upgrade your licence on renewal and you have met the Upgrading criteria detailed in this section, please forward your completed 2007 Competition Licence Application Form together with the appropriate licences and or Upgrade Card containing the signatures and the required payment to the Licence Section. If you want to upgrade your licence and you are already in possession of a current 2007 Competition Licence, please detach and complete the white licence amendment card contained in the Competitors' Year Book and forward it, together with your 2007 Competition Licence and any other appropriate licences and or Upgrade Card containing the necessary signatures with the required payment to the Licence Section. The payment is calculated as the difference between the cost of the existing licence and the new licence plus the upgrading fee as detailed in Section Z. A request for an upgrading signature has to be made to the organisers, and if the results of the event show that the driver's performance was satisfactory, his her Upgrade Card will be signed by the Clerk of the Course in the space provided. In the case of Kart Races, only the MSA Steward of the Meeting is empowered to sign and only one signature per meeting, per class is permitted, Kart Endurance or Kart Tyro signatures are not accepted to upgrade a Kart Race Licence ; . A maximum of two signatures may be obtained at a car race meeting. In exceptional circumstances only, documentary evidence, such as printed official results sheets may be accepted as proof of performance for upgrading. Results which predate the competitors last upgrade will only be accepted where the total number of results obtained is sufficient to meet the upgrade criteria from the basic competition licence for that discipline to that being sought. 2.15.1. RACING How to Retain a Licence Note: A competitor who is unable to retain their Race licence as mentioned below may be required to pass a course at an Association of Racing Drivers' School. Exemptions to this requirement are as detailed in 2.3.2. of this section. Competitors qualified to retain a National `A' or higher licence, who have not renewed their licence for 5 years or more will be required to pass the ARDS written examination. a ; A competitor who held a National `B' Race licence in any one of the years 2004, 2005 or 2006 may renew it for a 2007 National `B' Race licence. b ; A competitor who can provide proof of having ever held a National or National `A' Race licence may renew it for either a 2007 National `A' Race, International Historic Race or National `B' Race licence. c ; A competitor who can provide proof of ever having held an International Historic Race licence may renew it for a 2007 International Historic Race licence or a 2007 National `B' Race licence. d ; A competitor who can provide proof of ever having held an International `C' Race licence may renew it for a 2007 International `C' Race licence or a 2007 National `A' Race, International Historic Race or National `B' Race licence. e ; A competitor who can provide proof of ever having held an International `A' or `B' Race licence may renew it for a 2007 International `C' Race, National `A' Race, International Historic Race or National `B' Race licence. Special arrangements exist for retaining an International `A' or `B' licence and are contained in Appendix L of the FIA International Sporting Code. 2.15.2. RACING How to Upgrade a Licence Please note that Rallycross signatures are NOT acceptable for upgrading any Race licence. a ; National `B' to National `A' Race A competitor who is qualified to hold a 2007 National `B' Race licence may upgrade it to National `A' Race licence either at renewal or during the year as follows: Obtain Clerk of the Course's signatures on the Upgrade Card certifying that the qualifying events have been successfully completed. These are 6 National `B' or Clubman Races these can all be from one circuit ; , and must not contain more than 1 signature from Races organised by or on behalf of Racing Schools which form part of a school course or curriculum. One of the Clerk of the Course signatures required for having successfully completed a Race may be replaced by a Clerk of the Course signature recorded on the Upgrade Card for completing a day on a marshal's post during a race meeting. One of the Clerk of the Course signatures for having successfully completed a Race may be replaced with a signature recorded on the Upgrade Card for having successfully completed an ARDS Advanced Course. b ; National `A' to International `C' Race A competitor who is qualified to hold a 2007 National `A' Race licence may upgrade it to International `C' Race licence either at renewal or during the year as follows: Obtain Clerk of the Course's signatures on the Upgrade Card certifying that the qualifying events have been successfully completed. These are 3 National `A' Races OR 2 National `A' plus 2 National `B' or Clubman Races OR 6 National `B' or Clubman Races. In all options signatures must be obtained at 3 different venues. c ; International `C' to International `B' Race A competitor who is qualified to hold a 2007 International `C' Race licence may upgrade it to International `B' Race licence either at renewal or during the year in accordance with Appendix L of the FIA International Sporting Code. d ; International `B' to International `A' Race In accordance with Appendix L of the FIA International Sporting Code. e ; National `B' to International Historic Race.
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Objective: To compare the adverse event AE ; profile of the novel SSRI escitalopram the S-enantiomer of citalopram ; , to that of racemic citalopram. Methods: Recent placebo-controlled studies 8 weeks in duration ; with over 700 patients have demonstrated definitive efficacy for escitalopram 10-20mg day ; vs. placebo. Several trials also included a citalopram comparator. An analysis was performed on the AE profiles across these studies for escitalopram, citalopram, and placebo. AE profiles were also examined for the available short term 4-6 week duration ; placebo-controlled studies in depression with citalopram. Results: Results of this analysis, including specific clusters of AE's associated with activation, gastrointestinal tolerability, and autonomic function, and overall discontinuation rates due to AE's, will be presented. Conclusion: Preliminary analyses demonstrate that both drugs are well tolerated and are suggestive of an improved safety profile for escitalopram. References: J.P. Feighner, K. Overo 1999 ; : Multicenter, placebo-controlled, fixed-dose study of citalopram in moderate-to-severe depression, J Clin Psychiatry, 60: 824-30 J. Hyttel, K.P. Bogeso, J. Perregaard, C. Sanchez 1992 ; : The pharmacological effect of citalopram resides in the S ; - + ; -enantiomer, J Neural Transm Gen Sect., 88: 157-60.
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P., agonizing. Intense, torturing pain of mind or body. May be due to coronary thrombosis, angina pectoris, aortic aneurysm, mediastinitis. May occur in milder form in asthma, tracheobronchitis, or it may be due to referred pain from gallbladder, intestinal obstruction, diaphragmatic hernia, pancreatitis, or a perforated ulcer. P., boring. Pain deep in tissues that give the sensation of being produced by a boring instrument. P., Brodie's. Pain caused near a joint a infected with neuralgia when the skin is folded near it. P., causalgic. Spontaneous pain, esp burning in character, when associated with anesthesia or hyperesthesia in a giver nerve. SYN: causalgia. P., central. Pain due to a lesion in the central nervous system. P., chronic. The persistence of pain beyond the usual or expected course of an acute disease or after a reasonable time for an injury to heal has elapsed. P., chronic intractable. Chronic pain due to a known cause, such as malignancy, mental illness, or a neurological disorder. P., cramplike. Muscular spasm such as epigastric pain. Significance depends upon location of pain. Menstrual pain is often cramplike. P., dull. Continuous mild throbbing. P., eccentric. Pain occurring in peripheral structures due to a lesion involving posterior roots of spinal nerves. P., girdle, Pain resembling sensation of a constricting cord around the waist, occurring in spinal cord disease. P., intractable. Pain that cannot be easily relieved, as that occurring from certain neoplastic invasions. P., lancinating. A short, sharp, cutting pain. SYN: p., acute. P., mobile. Pain that moves from one area to another. P., movement. Kinesalgia, P., neuralgic. Pain, frequently paroxysmal, occurring along the branches of a nerve. Temporarily relieved by heat or pressure. May be rheumatic in origin. P., night. Pain in hip or knee during muscular relaxation in sleep. P., noise. Pain of ear caused by noise. SYN: odynacuses. P., objective. Pain induced by some external or internal irritant, by inflammation, or by injury to nerves, organs, or other tissues that interferes with the function, nutrition, or circulation of the affected part. Usually traceable to a definite pathological process. P., organic. Pain due to organic causes. P., osteocopic. Pain in bones. P., parenchymatous. Pain felt at the peripheral end of a nerve. P., paresthasic. Stinging or tingling sensation manifested in central and peripheral nerve lesions. P., phantom limb. Pain that seems to be in certain limb following amputation of that limb. P., pseudomyelic. False sensation of movement in a paralyzed limb or of no movement in a moving limb. Not a true pain. P., referred. Pain seeming to arise in an area other than its origin, as pain from appendicitis, which often seems to occur in areas other than that of the appendix. P., remittent. Pain with temporary abatements in severity. Characteristic of neuralgia and colic. P., rest. Pain due to ischemia that comes on when sitting or lying. P., shifting. Pain that seems to arise from different sites from time to time. Present in rheumatism, hysteria, and locomotor ataxia. P.'s, starting. Pains accompanied by muscular spasm during early stages of sleep and finasteride.
Data not shown ; . Table 1 shows tissue weights for the 120-dayold males. ATR or BROM affected none of these measures with the sole exception of the ventral prostates of the 6.25-mg kg ATR males, which were significantly greater than those of controls. However, when analyzed as a percent of body weight, this difference in the 6.25 mg kg ATR group was no longer significant. Treating the dams with oPRL on PND 14 resulted in a signifi.
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The eight-week, randomised, double blind study, which was conducted in 44 sites across eight european countries, showed that edcitalopram 10-20mg ; was at least as efficacious as venlafaxine xr 75-150mg ; , which is widely recognized as a very effective antidepressant and fluconazole and escitalopram.
Dron, an analog, mimics some actions 23 ; but is believed to exert fewer thyroid side effects due to the fact that it is completely devoid of iodine. To test whether this drug yet might reproduce the blocking effect of on 125I transport, Dron and its active metabolite DBDron were investigated. Thyroid cell toxicity was apparently higher with Dron than AM, and 50 m rapidly caused a loss of TER and detachment of cells with condensed nuclei designating apoptosis data not shown ; . However, 520 m Dron did not compromise cell viability and the epithelial barrier function remained intact throughout experiments. As shown in Fig. 6A, Dron dose-dependently inhibited the transepithelial 125 I transport Fig. 6A, upper panel ; and caused a slight increase in the cellular 125I content Fig. 6A, lower panel ; to about the same extent as did AM. In further similarity with the response to AM, the inhibited transport of 125I persisted 3 d after washout of Dron Fig. 6B ; . Moreover, nonlethal concentrations of DBDron and DEA, the major metabolite, were found to inhibit iodide transport as well Fig. 6C.
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Blind comparison of escitalopram and venlafaxine extended release in the treatment of major depressive disorder.
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Lung injury, nausea, rhinopharyngitis, syncope, testis disease, 702 erythropoietin, heart failure, absence of side effects, 923 escitalopram, generalized anxiety disorder, paroxetine, anorgasmia, diarrhea, fatigue, insomnia, somnolence, 753 - generalized anxiety disorder, relapse, anorexia, attention disturbance, backache, disease exacerbation, dizziness, drug induced headache, dyspnea, ejaculation disorder, fatigue, hyperhidrosis, insomnia, libido disorder, nausea, rhinitis, upper respiratory tract infection, xerostomia, 768 esophageal adenocarcinoma, antineoplastic agent, lower esophagus sphincter, bone marrow suppression, capecitabine, carboplatin, cisplatin, docetaxel, esophagitis, febrile neutropenia, fluorouracil, gastrointestinal symptom, hematologic disease, irinotecan, nausea, neutropenia, oxaliplatin, paclitaxel, platinum derivative, stomatitis, 1164 esophagus carcinoma, Barrett esophagus, esophagus function disorder, photofrin, 1208 esophagus function disorder, Barrett esophagus, esophagus carcinoma, photofrin, 1208 esophagus varices bleeding, cerebrovascular disease, recombinant blood clotting factor 7a, hemiparesis, hypesthesia, 1065 essential hypertension, lercanidipine, asthenia, edema, headache, 948 esthetics, dermatological agent, skin abrasion, hyperpigmentation, resorcinol, salicylic acid, skin allergy, thyroid disease, 904 estrogen, anastrozole, aromatase inhibitor, breast cancer, cancer hormone therapy, exemestane, letrozole, tamoxifen, androgen, arthralgia, cardiovascular disease, cataract, cerebrovascular accident, deep vein thrombosis, edema, endometrium cancer, estradiol, fracture, fulvestrant, gestagen, hot flush, hypercholesterolemia, jaundice, lung embolism, medroxyprogesterone, megestrol acetate, myalgia, nausea, obesity, osteoporosis, selective estrogen receptor modulator, stroke, thromboembolism, toremifene, vagina atrophy, vagina bleeding, vagina discharge, virilization, 1201 etanercept, adalimumab, infliximab, rheumatoid arthritis, drug hypersensitivity, headache, skin manifestation, tumor necrosis factor alpha antibody, 885 - corticosteroid, disease modifying antirheumatic drug, infliximab, recombinant interleukin 1 receptor blocking agent, rheumatoid arthritis, tuberculosis, 1279 - dermatomyositis, azathioprine, cyclosporin, cytotoxic agent, disease exacerbation, hybrid protein, immunoglobulin G1, methotrexate, muscle weakness, prednisone, rash, steroid, tumor necrosis factor alpha inhibitor, unspecified side effect, 1019 - drug hypersensitivity, influenza, influenza vaccination, influenza vaccine, rheumatoid arthritis, dipyrone, drug fever, drug induced disease, immediate type hypersensitivity, inactivated vaccine, injection site reaction, methotrexate, pneumonia, prednisolone, 1026 ethinylestradiol, oral contraception, artery thrombosis, thromboembolism, 1109 ethinylestradiol plus norelgestromin, desogestrel, hormonal contraception, levonorgestrel, norgestimate, occlusive cerebrovascular disease, oral contraception, oral contraceptive agent, vein thrombosis, cerebral venous sinus thrombosis, contraceptive agent, 1107 ethnic difference, drug induced disease, naratriptan, unspecified side effect, 823 etonogestrel, contraception, drug implant, vagina bleeding, 1108 etoposide, autologous stem cell transplantation, cancer combination chemotherapy, cyclophosphamide, dexamethasone, melphalan, nonhodgkin lymphoma, rituximab, abnormal substrate concentration in blood, bacteremia, bleeding, cardiovascular disease, diarrhea, febrile neutropenia, fever, hemorrhagic cystitis, hyponatremia, infection, lung disease, mucosa inflammation, nausea, nephrotoxicity, vomiting, 1175 etretin, subcorneal pustular dermatosis, chapped lips, 907 exemestane, anastrozole, aromatase inhibitor, breast cancer, Section 38 vol 42.2.
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