We acknowledge that our patients had undergone pretreatment with chemotherapy and may have had existing, subclinical damage that contributed to their visual disturbances. However, it is probable that high-dose irofulven treatment caused the cone-specific damage given the close temporal relationship of irofulven administration to the onset of symptoms and subsequent dramatic improvement of color vision and GVFs when irofulven treatment was discontinued. Accordingly, the manufacturer has modified the dosage because of the visual disturbances. Rankin and Pitts7 described 2 patients with pigmentary maculopathy and optic neuropathy secondary to carboplatin treatment. Our patients received carboplatin treatment, but did not have optic neuropathy or pigmentary maculopathy by funduscopic, gross, or histopathologic examination. Katz et al18 described a patient that inadvertently received a 4-fold dose of cisplatin and developed significant antemortem vision loss in both eyes. That patient demonstrated nearly flat photopic and scotopic ERG responses. Histopathologic features revealed a split outer plexiform layer, but cones and rods were intact, suggesting that cisplatin therapy does not cause cone cell death. Paraneoplastic retinopathy, 19, 20 including specific cone loss only, develops in some patients with cancer.21, 22 However, the serum samples of patients 1 and 2 lacked antirecoverin antibodies and their retinas had relatively normal rod function, which is typically lost in cancerassociated retinopathy.19 Prospective ophthalmologic, perimetric, and ERG testing are ongoing in patients treated with irofulven before and after dose reduction in the amended protocol. Results of our microscopic study of the retinas from a patient treated with irofulven demonstrated marked loss of cones with relative sparing of rods. High-dose irofulven treatment seems to be associated with a clinical picture consistent with cone damage, confirmed by ERG testing and histopathologic findings. Submitted for Publication: March 8, 2004; final revision received August 17, 2004; accepted September 22, 2004. Correspondence: Michael S. Lee, MD, Cole Eye Institute i-32, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44124 leem4 ccf ; . Funding Support: This study was supported by funds from MGI Pharma, Inc, Bloomington, Minn, and The Foundation Fighting Blindness, Owings Mills, Md. Previous Presentations: Presented in part at the North American Neuro-Ophthalmology Society Annual Meeting; Copper Mountain, Colo; February 13, 2002; and the Association for Research in Vision and Ophthalmology; Fort Lauderdale, Fla; May 4, 2003.
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Medroxyprogesterone acetate. 29 medroxyprogesterone acetate 150 mg mL. 27 mefloquine.10 MEGACE ES.13 megestrol acetate. 13 meloxicam.7 MENINGOCOCCAL POLYSACCHARIDE VACCINE. 35 mercaptopurine. 15 mesalamine rectal susp. 31 mesna inj. 16 MESNEX tabs 400 mg. 16 MESTINON syrup. 24 MESTINON TIMESPAN. 24 metformin.25 metformin ext-rel. 25 methazolamide.43 methimazole. 29 methocarbamol. 24 methocarbamol aspirin. 24 methotrexate. 14 methotrexate 2.5 mg. 15, 34 methotrexate inj.34 methyldopa.19 methylphenidate.23 methylphenidate ext-rel.23 methylprednisolone.29 methylprednisolone inj 40 mg, 125 mg, 1000 mg.29 metipranolol.43 metoclopramide.30 metoclopramide inj. 30 metolazone. 19 metoprolol. 18 metoprolol inj.18 metoprolol hydrochlorothiazide.18 METROGEL.41 METROGEL-VAGINAL. 33 metronidazole. 12 metronidazole crm, gel, lotion. 41 metronidazole inj. 12 metronidazole vaginal gel. 33 mexiletine.17 MIACALCIN. 26 midodrine. 19 MIGRANAL spray.23 minocycline.10 minoxidil.19 MIRAPEX. 22 mirtazapine.21 misoprostol. 32 mitomycin.14 mitoxantrone inj. 15 MOBAN.22 mometasone crm, lotion, oint 0.1%. 40 morphine ext-rel. 7 MORPHINE inj. 8 morphine soln. 8 MORPHINE soln. 8 MORPHINE soluble tabs 10 mg. 8 morphine sulfate immediate release.8 morphine supp. 8 MUMPS VIRUS VACCINE LIVE ; .35 mupirocin oint. 39 MUSTARGEN. 13 MYCOBUTIN. 11 nabumetone. 7 nadolol. 18 nafcillin inj.9 naloxone inj. 24.
Vital statistics Integrated Development Indicators System SID ; System of indicators with gender perspective Living standards survey 1. 2. 3. Births Deaths Nutrition Equality between the sexes 5. Health care, drinking water and sanitation coverage 6. Age 7. Ethnicity 8. Territoriality 9. Urban Rural 10. Social development 11. Democracy.
Intervention Arm 1 MPH plus non drug intervention Average of 22 mg day with a maximum of 30mg and minimum of 10mg; administered twice daily am, noon ; . Parent training involved sessions and group meetings on child management, and learning how to co-operate efficiently with school personnel. [Administered by parent and Medical Personnel] Arm 2 Placebo plus non drug intervention Parent training [Administered by parent and Medical Personnel] Arm 3 Methylpehnidate Hydrochloride [MPH] Average of 22 mg day with a maximum of 30mg and minimum of 10mg; administered twice daily am, noon ; . [Administered by parent].
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Marie-Paule V Austin and Philip B Mitchell 1998 ; . Psychotropic medications in pregnant women: treatment dilemmas. Med J Australia 169: 428-431 and methylprednisolone.
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For example, treatments of psychiatric disorders observes that cocaine, amphetamines, and methylphenidate are neuropharmacologically alike american psychiatric association 1989, 1221.
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LLanguage A rant against jargon and neologisms Young ; E ; 155 Learning disorders Efficacy of methylphenidate in children with attention-deficit hyperactivity disorder and learning disabilities: a randomized crossover trial Grizenko and others ; Res ; 46 Levomepromazine Levopromazine versus chlorpromazine in treatment-resistant schizophrenia: a double-blind randomized trial Lal and others ; Res ; 271 Lexical processing About the mechanisms of auditory verbal hallucinations: a positron emission tomographic study Stephane and others ; Res ; 396 Lithium The effect of lithium on the adrenoceptor-mediated second messenger system in the rat brain Devaki and others ; Res ; 246 Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania Frey and others ; Res ; 326 Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal cortex of subjects with bipolar disorder Sun and others ; Res ; 189 Is the thyroid still important in major depression? Joffe ; E ; 367.
Free Meet Tom Gardner, D.Ph., and learn about common side effects of medications at this free HealthLink Plus class. Bring a list of your own medications for review by Dr. Gardner. Women's East Campus: Tuesday, Jan. 17, 5: 30 to 6: p.m. Northgate Mall: Tuesday, Feb. 21, 5: 30 to 6: p.m. To register, call 423-778-LINK 5465 and miacalcin.
Nicholas Piramal India Ltd has been able to come to the terms with the changing dynamics of the industry and has emerged as a leader in the contract manufacturing space. The company has earned the status of 'Partner of Choice' from global life science companies, which has helped the company to continuously improve its earning quality and move on the steady growth trajectory. Nicholas was the forerunner to envisage the huge opportunities in the pharmaceutical outsourcing space and has made significant investments in domestic formulations field force, a new state-of-the-art integrated R&D center, API and formulations assets for the custom manufacturing business and acquisitions. Over the past few years, the company's focus has been skewed towards the contract manufacturing business. It is also aggressive on ramping up the pathology business. In the domestic formulation business about 50% of its sales ; , it expects to achieve a reasonable growth of 10-12% for the couple of years. We view Nicholas as the best play on the custom manufacturing services, which we believe is a large and high growth business. We initiate our coverage with a BUY recommendation.
References Beatty WW, Blanco CR, Hames KA, Nixon SJ 1997 ; . Spatial cognition in alcoholics: influence of concurrent abuse of other drugs. Drug Alcohol Depend, 44: 167-174. Blattler R, Dobler-Mikola A, Steffen T, Uchtenhagen A 2002 ; . Decreasing intravenous cocaine use in opiate users treated with prescribed heroin. Soz Praventivmed.; 47 1 ; : 24-32 Bleich A, Gelkopf M, Schmidt V, Hayward R, Bodner G, Adelson M 1999 ; . Correlates of benzodiazepine abuse in methadone maintenance treatment. A 1 year prospective study in an Israeli clinic. Addiction, 94: 1533-40 Bovasso G, Cacciola J 2003 ; . The long-term outcomes of drug use by methadone maintenance patients. J Behav Health Serv Res, 30: 290-303 Caplehorn JR, Drummer OH 2002 ; . Fatal methadone toxicity: signs and circumstances. Aust N Z J Public Health, 26: 358-362 Cole JC, Bailey M, Sumnall HR, Wagstaff GF, King LA 2002 ; . The content of ecstasy tablets: implications for the study of their long-term effects. Addiction, 97: 1531-1536 Darke S, Hall W, Ross M, Wodak A 1992 ; . Benzodiazepine use and HIV risk-taking behaviour among injecting drug users. Drug Alcohol Depend, 31: 31-36 EMCDDA 2002 ; . 2002 Annual report on the state of the drugs problem in the European Union Epstein DH, Preston KL 2003 ; . Does cannabis use predict poor outcome for heroindependent patients on maintenance treatment? Past findings and more evidence against. Addiction, 98: 269-279 Gossop M, Marsden J, Stewart D, Kidd T 2003 ; . The National Treatment Outcome Research Study NTORS ; : 4-5 year follow-up results. Addiction, 98: 291-303 Kriener, H., Billet, R., Gollner, C., Lachout, S., Neubauer, P., Schmid, R. 2001 ; : An inventory of on-site pill testing interventions in the EU, EMCDDA, Lisbon. Koesters SC, Rogers PD, Rajasingham CR 2002 ; . MDMA 'ecstasy' ; and other 'club drugs'. The new epidemic. Pediatr Clin North Am, 49: 415-433. Kolar AF, Brown BS, Weddington WW, Ball JC 1991 ; . A treatment crisis: cocaine use by clients in methadone maintenance programs. NIDA Res Monogr, 105: 365-366. Landheim AS, Bakken K, Vaglum P 2003 ; . Gender differences in the prevalence of symptom disorders and personality disorders among poly-substance abusers and pure alcoholics. Substance abusers treated in two counties in Norway. Eur Addict Res, 9: 8-17 Leri F, Bruneau J, Stewart J 2003 ; . Understanding polydrug use: review of heroin and cocaine co-use. Addiction, 98: 7-22 Levin FR, Evans SM, McDowell DM, Kleber HD 1998 ; . Methyllphenidate treatment for cocaine abusers with adult attention-deficit hyperactivity disorder: a pilot study. J Clin Psychiatry, 59: 300-305 and monopril.
Previous characterizations of West Nile fever have generally described it as a mild, acute syndrome lasting 3 to 6 days and consisting of fever, malaise, headache, myalgia, nausea, vomiting, and rash.Our findings indicate that West Nile fever can often be more severe than previously recognized. In patients we interviewed, the median time needed to recover to a point considered "back to normal" was 60 days. In addition, approximately one third of the patients in our study required hospitalization and half could not attend school or work for 10 days." - Annals of Internal Medicine 2004; 141: 360-65; annals.
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CD-ROMs on several topics are now available for patients and visitors to view at The Learning Center. The topics include breast cancer, ovarian cancer, coping with cancer and nutrition. The Learning Center also provides the latest information about health, cancer and cancer prevention. Resources available include brochures, general reference and health books, medical reference books, Internet access for medical and health information, audio and videotapes, medical journals and newsletters, and medical and consumer health databases. Books and videos are also sold. The Learning Center is located on the fourth floor of the Rose Zone R4.1100 ; across from the RC elevators. It is open Monday-Friday 9 a.m.-4 p.m., Thursday 9 a.m.-7 p.m. For more information, call 713 ; 7458063 and naproxen.
As we saw in 7 ; above, different specific senses of window have to be activated unless we are to encounter a zeugmatic effect, but even though aunt may have specific reference either to a maternal aunt or a paternal aunt, both are acceptable at the same time, as are different combinations of the two. In my opinion, this would lead us to consider window as involving elements of both monosemy vagueness and polysemy ambiguity, and would be located somewhere in between aunt and paint on my continuum see fig. 4: 3 ; . Lakoff 1987: 417-418 ; , however, considers window to be polysemous, with three basic senses referring to the opening in the wall, the frame, and the glass panes, respectively. Metonymic processes may thus result in expressions of varying degree of polysemy, but on the whole, extensions based on metonymy tend to lead to senses that are more vague less ambiguous compared to metaphorical extensions, and they would therefore typically be found to the left of metaphorical extensions on my scale. However, simply labelling a word as polysemous or monosemous is of less interest than describing the relations that hold between different senses in as much detail as possible cf. Langacker 1991: 268 ; , which can be achieved if we consider them as forming part of a continuum. This allows us to see the connection between the traditional division into polysemous words with distinct senses, on the one hand, and monosemous, for example, methylph4nidate dextroamphetamine.
With considerable morbidity and mortality.1, 2 Surgical reexploration due to excessive bleeding has been associated with a threefold to fourfold increase in mortality and with multiple morbidities, including renal failure, sepsis, atrial arrhythmias, prolonged mechanical ventilatory support, and increased length of hospital stay.3 Thus, safe and effective strategies to prevent and treat postoperative bleeding are crucial. Limitations of Currently Available Pharmacologic Agents Blood products are often used to correct the anemia that ensues and to promote hemostasis. Fresh-frozen plasma, pooled platelets, and cryoprecipitates replenish clotting factors and other important mediators of the clotting cascade, and are helpful in restoring hemostasis. However, the administration of blood products in this setting has several limitations, including a relatively high rate of transClinical Investigations and nasonex.
Sleep Apnea can generally be treated very effectively once properly diagnosed and categorized as to type and severity. Treatments for each type of sleep apnea may include: Obstructive sleep apnea Weight loss Surgery to remove airway blockage The nasal CPAP machine Continuous Positive Airway Pressure ; , a device worn over the nose that is attached to an air compressor which keeps airways open. Dental appliances Central sleep apnea Medications, BiPAP, CPAP Mixed sleep apnea The same as for obstructive apnea.
Received September 26, 2000; final revision received December 7, 2000; accepted December 11, 2000. From the Departments of Anesthesiology and Critical Care Medicine N.J.A., R.J.T., M.J.W., P.D.H. ; and Neurology L.D.M. ; , Johns Hopkins University School of Medicine, Baltimore, Md. Correspondence to Patricia D. Hurn, PhD, Departments of Anesthesiology Critical Care Medicine, 600 N Wolfe St, Blalock 1404, Johns Hopkins University School of Medicine, Baltimore, MD 21287-4961. E-mail phurn jhmi 2001 American Heart Association, Inc. Stroke is available at : strokeaha and neurontin.
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This is to support the caregivers and help them support each other in their work in taking care of patients. I was very impressed with the quality of the discussion last week that we had. Your staff is absolutely terrific. They are wonderful in their kindness and generosity towards the patient who was being discussed, as well as towards each other. The notion of the Schwartz rounds is to begin to look at this interpersonal, psychological, social dimension of provision of care, both among the caregivers and between the caregivers and the patients. Chu That is an important issue because one of our pediatric oncologists, Dr. Nina KadanLottick here at Yale Cancer Center recently published an article looking at the risk of psychiatric illness in cancer patients. What was astonishing to me was that over half of the patients who had a major psychiatric disorder had not received any type of mental health services. So it's clearly something that we need to pay closer attention to. I was impressed with that study. It revealed that almost 12-15% of the patients had a diagnosis of major depression, and probably many more than that had subsyndromal depression which is what we call it when it doesn't quite qualify. But the experience of being demoralized is a major part of getting the news about cancer, and how one deals with that, I'm sure has a lot to do with the outcome in terms of whether or not things can go better. My father, for instance, died of a hypernephroma. He became very demoralized by having the diagnosis and his course of illness was very brief as a result. I have had other relatives who have done extremely well in these kinds of circumstances. I want to share with you another email that we received from Barbara who lives in Greenwich, Connecticut. She writes: I had very early breast cancer a few years ago and have been left since then with a lot of worry and a lot of concern for the future. As I listen to this discussion, I thinking, is this demoralization or depression, or maybe a little bit of both? Miller What are some strategies for people, not just Barbara who indicated she is in her late 40s, but at different times of life. Are there different coping strategies that are helpful? Yes, obviously the experience of an illness like cancer is very different for a child or an adolescent or young adult or someone who is older. Certainly one of the important things to do is talk about it, try to develop a clear idea of what this illness means to you at this time in your life. Some cancers are not necessarily associated with mortality or reduced mortality, and some of the issues are more about disfigurement or loss of function of one sort or another. So it's very important for the person who has the diagnosis freshly to have a chance to explore what it means to them. We are going to pause in a minute for a survivorship story that we are really pleased to share with you. I going to remind our listeners to please email your questions to Healthline yale . Again, we would love to be able to respond to your questions. We are going to take a break for a survivorship story. A few years ago the diagnosis of cancer was a death sentence for many patients, but today thanks to advances in clinical research, we are turning the corner in the battle against cancer. There are over 10, 000, 000 cancer survivors now living in the United and norvasc and methylphenidate, for example, methylphenjdate drug test.
Usually occurring in hospitalized patients, these cutaneous problems can include major abscesses, postsurgical skin wound infections, and infected ulcers. The infections are usually caused by susceptible strains of gram-positive microorganisms, such as Staphylococcus aureus including methicillin-resistant strains ; , Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus dysgalactiae subspecies equisimilis, and Enterococcus faecalis vancomycinsusceptible strains only ; . Cubicin is not indicated for the treatment of pneumonia. Cubicin is the first approved product in a new class of antibiotics called cyclic lipopeptide antibacterial agents and treats infections in a way that is distinct from any other antibiotic. The FDA based its approval on a review of clinical studies involving more than 1, 400 adults. The studies demonstrated that Cubicin was equivalent to other standard treatments. Most reported adverse events were mild to moderate in intensity, such as gastrointestinal disorders, injection-site reactions, fever, headache, insomnia, dizziness, and rash. Blood tests showing muscle injur y were rarely found in patients in clinical trials. Most of these patients had no symptoms, and values returned to normal after therapy. Patients receiving Cubicin should be monitored for the development of muscle pain or weakness, and creatine phosphokinase levels should be assessed weekly. The manufacturer expects the medication to be available by early November 2003. Sources: FDA Talk Paper, September 12, 2003; fda.gov; Dow Jones Business News, September 12, 2003; cubist.
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Characterized by a reduced ability to maintain and shift attention appropriately, but the cognitive deficits tend to fluctuate, while those of dementia tend to be stable or progressive. An amnestic disorder is characterized by memory impairment without significant impairment in other cognitive domains. Mental retardation has an onset before age 18 and is characterized by significantly subaverage general intellectual functioning, which does not necessarily include memory impairment. Schizophrenia may be associated with multiple cognitive impairments and a decline in functioning, but the cognitive impairment tends to be less severe and occurs against a background of psychotic and behavioral symptoms meeting the established diagnostic criteria. Particularly in elderly persons, major depressive disorder may be associated with complaints of memory impairment, difficulty concentrating, and a reduction in intellectual abilities shown by history or mental status examination; this is sometimes referred to as pseudodementia. The two may sometimes be distinguished on the basis of an assessment of the course and onset of depressive and cognitive symptoms and by response to treatment of the depression. However, even when the onset of depressive symptoms precedes or coincides with the onset of cognitive symptoms and both resolve with antidepressant treatment, as many as one-half of patients go on to develop an irreversible dementia within 3 years 2 ; . Dementia must be distinguished from malingering and factitious disorder, which generally manifest patterns of cognitive deficits that are inconsistent over time and are uncharacteristic of those typically seen in dementia. Dementia must also be distinguished from age-related cognitive decline, the mild decline in cognitive functioning that may occur with aging, which is nonprogressive and does not lead to functional impairment.
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The Council congratulates Emeritus Professor Arthur Neil Bruere in his appointment as an officer of the New Zealand Order of Merit ONZM ; . For services to veterinary science. Professor Bruere has practised and taught veterinary science for over 50 years and is a recognised authority on cytogenetics and livestock health. He taught at Massey University for over 20 years, was foundation Professor of Veterinary Medicine and Clinical Pharmacology and head of the Veterinary Clinical Sciences Department for nine years until he retired in 1988. He was a foundation member of the Sheep and Beef Cattle Veterinarians Association of the New Zealand Veterinary Association and served as president on two occasions. He was awarded the Association's Alan Baldry International Crook for Service to the sheep industry and made a life member. In 2005 he received the President's Award of the New Zealand Veterinary Association. He has also received the Australian College of Veterinary Scientists medal in 1985. Professor Buere has contributed to numerous publications and conferences and was author of several texts on sheep health and veterinary toxicology. He was the driver behind and collator of the Roll of Honour of Veterinarians, printed recently in Vetscript.
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OMAP will require PA on doses above the recommendations when they are not prescribed by a psychiatrist. We will approve PA requests from non-psychiatric prescribers for children up to 2mg kg for methylphenidate and 0.5mg kg for amphetamines. 1 & 2 We will evaluate doses above these recommendations on a case-bycase basis. Call 1-800-344-9180 for OHP fee-for-service PA requests. Table 1. Maximum recommended doses for stimulants and methylprednisolone.
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DaytranaTM patch approved to treat ADHD. DaytranaTM methylphenidate transdermal system ; is the first and only nonoral prescription medication for the treatment of ADHD. The patch, about half the size of a credit card, is applied once daily and delivers up to a nine-hour dose of methylphenidate. This new delivery system may be especially helpful for parents of children who require multiple bottles of their ADHD medication for school, daycare, home, etc. Helping patients enrolled in multiple Part D plans: Up to one million beneficiaries mostly dual eligibles ; may be enrolled in more than one Part D plan. Because patients should only be using one plan, the Centers for Medicare and Medicaid Services CMS ; has sent green notices to these patients outlining what they must do to remain in the plan of their choice. Pharmacists may already be seeing patients with these green notices. To help patients interpret them, read the one-page summary available at nacds medicareimplementation.
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American Psychiatric Association. 1994 ; . Diagnostic and statistical manual of mental disorders 4th edition ; . Washington, DC: Author. Attanasio, P., Jacobs, K., Singer, B., & Shore, D. Executive Producers ; 2006 ; . House [Television series]. New York: Fox Broadcasting Company. Barkley, R. A. 2006 ; Attention Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. 3rd ed. ; . New York: Guilford. Barrett, S. P., Darredeau, C., Bordy, L. E., Pihl, R. O. 1995 ; . Characteristics of methylphenidate misuse in a university student sample. Canadian Journal of Psychiatry, 50, 557-461. Barrett, S. P. & Pihl, R. O. 2002 ; Oral methylphenidatealcohol co-abuse. Journal of Clinical Psychopharmacology, 22, 633634. Binder, L. M. 1992 ; . Deception and malingering. In A. E. Puente & R. J. McCaffrey Eds. ; , Handbook of neuropsychological assessment: A biopsychosocial perspective Critical issues in neuropsychology ; pp. 353-374 ; . New York, NY: Plenum Press. Breggin, P. and Breggin, G.R. 1995 ; . The Hazards of Treating "Attention-Deficit Hyperactivity Disorder" with Methylphenifate Ritalin ; . The Journal of College Student Psychotherapy, 10 2 ; , 55-72. Brown, T. E. 1996 ; . Brown ADD Scales. San Antonio, TX: The Psychological Corporation, Harcourt, Brace and Company. Burt, J. 2004, November 8 ; . If you get a bad lottery number, don't get mad get sick. Columbia Daily Spectator. Retrieved February 24, 2006 from : columbiaspectator Butcher, J. N., Dahlstrom, W. G., Graham, J. R., Tellegen, A., & Kaemmer, B. 1989 ; . MMPI-2: Minnesota Multiphasic Personality Inventory-2: Manual for administration and scoring.
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