More than 88% of the subjects exposed underwent three apheresis 2 days prior to each infusion of study product and received the scheduled 3 infusions of the APC8015 or APCPlacebo every two weeks. All subjects were followed until 36 months or death, whichever came first. Table 24 shows the number of infusions subjects received. The vast majority of subjects received 3 infusions as per protocol 88.4% in APC8015 arm and 91% in APC-Placebo arm.
8840 Bird Road, Suite 400 Health Resource Center How Emotions Affect Your Physical Health. Thursday, Jan. 8, 10: 30-11: a.m., Dr. Kimberly Kiddoo, psychologist. Headache or Back Pain: Can Botox Help You? Tuesday, Jan. 20, 7-8 p.m., Dr. Allan Herskowitz, neurologist. A Laugh a Day Keeps the Doctor Away in Spanish ; . Tuesday, Jan. 27, 10: 30-11: a.m., Dr. Gilda Moreno, psychologist. Oh, My Aching Feet. Thursday, Feb. 12, 1-2 p.m., Dr. Michael Cook, podiatrist. Relief for Low Back Pain in Spanish ; . Tuesday, Feb. 17, 10: 30-11: a.m., Dr. Enrique Monasterio, rehabilitation specialist. To register, call 786-596-3814.
For renal or lung transplantation as both renal and pulmonary functions are stable. The presence of advanced retinopathy is not surprising as a high proportion of patients with diabetic nephropathy at the time of diagnosis show evidence of retinopathy. Despite aggressive laser therapy, retinal damage has progressed and vision is threatened. Two manifestations of autonomic neuropathy have developed subsequent to the documentation of diabetic nephropathy and retinopathy, including delayed gastric emptying and orthostatic hypotension during periods of high ambient temperature. Vomiting as a result of poor gastric motility has been controlled by omeprazole and erythromycin. This case has been a catalyst for establishing a tri-monthly CF-endocrine clinic CF physician, endocrinologist, nurse specialist and dietitian ; to optimize CFRD management, to identify microvascular complications and to provide a focus for education. Contrary to standard diabetic dietary management, calorie avoidance, in particular fat and carbohydrate restriction, is not indicated and increased insulin should be used to manage increased caloric intake [1]. Protein intake reduction should be avoided due to the risk of malnutrition. Specific advice to the patient can include attempting to slow the rate of carbohydrate absorption which can be achieved by adding fat to the diet, ensuring an even spread of carbohydrate through the day and encouraging a complete carbohydrate intake. In conclusion, with an increasing incidence of CFRD due to improved survival, the effective identification, management and monitoring of CFRD is important in the care of patients with CF. Significant asymptomatic end-organ damage is not often suspected, and needs to be actively looked for.
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Symptoms First described by Gougerot and Carteaud in 19271 as one of the primary papillomatoses, CRP is usually an asymptomatic dermatosis of unknown etiology.2 The majority of cases are sporadic though familial cases have been reported in the literature.3, 4 Onset typically occurs in adolescence or early adulthood5 with a mean age of 21 years old. 6 It has a gender and racial predilection occurring 2.5x and 2x more often in women and blacks respectively.7 The primary lesion as described by Gougerot and Carteaud is a 1-2mm red papule that turns gray then brown attaining a size of 4-5mm.8 Initial sites of involvement include the intermammary, 11 interscapular, 12 and epigastric regions.8 The papules then increase in number and merge, becoming confluent centrally 2, 8 forming a rhomboid pattern with the long axis running cephalocaudally.13 There is also peripheral centrifugal spread9 with fading of the lesions into normal skin forming a reticulate pattern, hence the name CRP.10 Areas of this peripheral extension may include the face and neck, 10 axilla, 7 abdomen, and extremities though to a lesser extent.15 Accentuation of skin folds of the neck and axilla has been observed, 6 and no oral lesions are noted.2 Lesions are usually asymptomatic with pruritis occurring occasionally.10 In short, CRP classically presents with multiple brown, scaling papules and plaques in mainly a seborrheic distribution16 with confluence centrally and reticulation peripherally.
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A crucial step in a systems approach to drug discovery is to describe diseases not by symptoms but in the molecular language that `drug hunters' can act on. Additionally, to discover and develop new medicines with improved efficacy and reduced side effects for common multi-factorial, system-wide diseases, such as type 2 diabetes and cardiovascular disease, it is essential to generate comprehensive molecular descriptions of the disease and the responses to drugs so that the breadth of biochemical changes contributing to a disease or drug response can be taken into account. In this article, `systems pathology' is used to refer to the body-system-wide, predominantly molecular, characterization of a disease state relative to a healthy state and darvon, for example, libidus.
| Cialis generic usaSponses similar to those associated with asthma. Specifically, 5-lipoxygenase products can cause tissue edema10, 11 and migration of eosinophils12, 13 and can stimulate airway secretions.14, 15 The leukotrienes also stimulate cell cycling and proliferation of both smooth muscle and various hematopoietic cells16-19; these observations provide further evidence of a potential role of leukotriene modifiers in altering the biology of the airway wall in asthma. Since all these responses contribute to asthma, the pharmaceutical industry initiated research programs to identify substances that could inhibit the action or synthesis of the leukotrienes. By early 1998, three chemically distinct cysteinyl leukotriene-receptor antagonists and an inhibitor of leukotriene synthesis were available by prescription in more than a dozen countries Table 1 ; . In this article, we will review the biochemistry of the cysteinyl leukotrienes and the drugs that decrease the production or action of leukotrienes, with special attention to the effect of these drugs on laboratory-induced and chronic stable asthma.
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Effective November 1, 1993, certain Medicaid recipients may be asked to contribute to the cost of some medical services items. Notices are being sent out to all providers advising them of full implementation of recipient co-payments Attachment #3 and #4 ; . The attached Dear Medicaid Recipient letter explaining the new program requirements will be mailed by the Department in early October, 1993 to the heads of households in all Public Assistance and Medical Assistance Only cases determined eligible as of September 18, 1993 with an effective eligibility date of October 1, 1993 Attachment #1 ; . These are being provided to you for informational purposes only. Effective September 20, 1993, local districts must distribute the attached Medicaid Co-Payment Fact Sheet Attachment #2 ; with the application packet provided to all PA and MA Only applicants. Revised Client Booklets are being developed by the Department to include co-payment information and when you receive them, distribution of the fact sheet to new applicants will no longer be required. Additionally, local districts should note that copayments are to be applied towards a recipient's monthly spenddown when determining financial eligibility for Medical Assistance. Recipients have been instructed to save all co-payment receipts see Attachment #1 ; to verify the dollar amount which may be applied to reduce the spenddown. Following are the major highlights of the co-payment program. attached documents for further details on the program. A. Co-payments will apply to the following services only: o Inpatient hospital services provided by Article 28 facilities, hospitals with dual certification Article 28 and Article 31 ; , and out of state hospitals; Outpatient hospital and free-standing clinic; Non-emergency non-urgent visits to emergency rooms ER Drugs Exceptions: 1. psychotropic drugs, as defined by the Department, 2. family planning drugs, 3. FDA approved drugs for the treatment of TB Enteral and Parenteral formulae supplies; Medical surgical supplies except family planning items Laboratory services except when provided by physicians who bill directly and are not licensed as a provider of laboratory services X-ray services physicians ; . except when the service is provided by Refer to the.
| How do I request an exception to the Affinity Medicare Formulary? You can ask Affinity to make an exception to our coverage rules. There are several types of exceptions that you can ask us to make. You can ask us to cover your drug even if it is not on our formulary. 4 and desyrel.
Ordinator will also receive a copy of the completed seamless care documents. The community pharmacist will review the seamless care form and compare it with the medication profile prior to admission. At this point he she will be able to easily identify DRPs e.g. drug duplication because a new medication is to replace an old one, unnecessary medication on community pharmacy profile because condition was managed in the hospital, etc. ; . The community pharmacist will solve the problems he she identified and the DRPs unresolved by the hospital pharmacist and will document this on an easy-to-use check-box form. These documents will also be sent to the project coordinator. Satisfaction questionnaires will be mailed to the patient by the project coordinator two weeks following discharge from the hospital.
When drugs are prescribed in this off-label fashion, they are not subject to the usual fda testing process, and women who haven't given their informed consent to taking the drug become unwitting experimental subjects of ad hoc, unorganized, informal-and usually unpublished-research and famvir.
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Drug48 | -4.276294 .010195 -419.45 0.000 -4.296281 -4.256307 drug49 | dropped ; drug50 | -2.563089 .0118475 -216.34 0.000 -2.586315 -2.539862 drug51 | dropped ; drug52 | 1.085392 .0080543 134.76 0.000 1.069602 1.101182 drug53 | -.4997912 .0094145 -53.09 0.000 -.5182479 -.4813346 drug54 | -.5302009 .0128379 -41.30 0.000 -.555369 -.5050327 drug55 | -2.922594 .0116631 -250.58 0.000 -2.945459 -2.899729 drug56 | 1.366066 .0205686 66.42 0.000 1.325742 1.40639 drug57 | -1.261438 .010363 -121.73 0.000 -1.281754 -1.241122 drug58 | 2.681419 .0091142 294.20 0.000 2.663551 2.699287 drug59 | 3.720116 .0103533 359.32 0.000 3.699819 3.740413 drug60 | -4.65371 .0105557 -440.87 0.000 -4.674404 -4.633016 drug61 | -3.316207 .0094934 -349.32 0.000 -3.334818 -3.297595 drug62 | -3.34142 .0106104 -314.92 0.000 -3.362221 -3.320619 drug63 | -.440276 .0081077 -54.30 0.000 -.4561708 -.4243812 drug64 | -4.835184 .012664 -381.80 0.000 -4.860011 -4.810357 drug65 | 2.31856 .086477 26.81 0.000 2.149026 2.488094 drug66 | -.7156838 .0133707 -53.53 0.000 -.7418964 -.6894712 drug67 | dropped ; drug68 | -.7819502 .0111049 -70.42 0.000 -.8037207 -.7601796 drug69 | -3.561285 .0140689 -253.13 0.000 -3.588866 -3.533703 drug70 | dropped ; drug71 | -1.866035 .0095125 -196.17 0.000 -1.884684 -1.847386 drug72 | -.5060657 .0163938 -30.87 0.000 -.5382051 -.4739263 drug73 | 6.605538 .0273584 241.44 0.000 6.551903 6.659173 drug74 | -2.429198 .0110348 -220.14 0.000 -2.450831 -2.407565 drug75 | -2.084969 .0087464 -238.38 0.000 -2.102116 -2.067822 drug76 | -3.699753 .0139224 -265.74 0.000 -3.727047 -3.672458 drug77 | dropped ; drug78 | 3.303435 .0189211 174.59 0.000 3.266341 3.340529 drug79 | -3.893781 .0095568 -407.44 0.000 -3.912517 -3.875046 drug80 | -1.211651 .0075129 -161.28 0.000 -1.226379 -1.196922 drug81 | dropped ; drug82 | -.2522375 .0120597 -20.92 0.000 -.27588 -.2285949 drug83 | dropped ; cons | -1.603429 .0072581 -220.92 0.000 -1.617658 -1.5892 and imovane.
Medica Foundation, Amsterdam, The Netherlands ; , pp. 430-439. 21. Rasmussen, H. 1973 ; Mt. Sinai J. Med. New York 40, because cialis vs viagra.
Forsch Komplementarmed. 2006 Feb; 13 Suppl 1: 13-7. Epub 2006 Feb 17. Anti-inflammatory mechanisms of the Tibetan herbal preparation Padma 28 in the vessel wall. Exner M, Raith M, Holzer G, Gmeiner B, Wagner O, Kapiotis S. Klinisches Institut fr Medizinische und Chemische Labordiagnostik, Institut fr Medizinische Chemie, Medizinische Universitt Wien, Austria. markus.exner meduniwien BACKGROUND: The Tibetan herbal preparation Padma 28 has been shown to act as an anti-atherosclerotic agent in advanced peripheral arterial occlusive disease. We tested the effect of aqueous Padma 28 extracts on both the Creactive protein CRP ; induced expression of the pro-inflammatory cell adhesion molecule Eselectin and the anti-atherosclerotic protective enzyme heme oxygenase- 1 HO-1 ; in human aortic endothelial cells. METHODS AND RESULTS: According to FACS analysis, quantitative RT-PCR and Western blot, CRPinduced E-selectin expression was completely prevented by aqueous Padma 28 extracts. Additionally, Padma 28 mediated an up to 60-fold upregulation of HO-1 mRNA as measured by quantitative RT-PCR. This upregulation could also be demonstrated on the protein level. CONCLUSION: Aqueous extracts of the Tibetan herbal preparation Padma 28 inhibit CRP-induced expression of the inflammatory cell adhesion molecule Eselectin and lead to upregulation of the vascular protective enzyme HO-1 in human aortic endothelial cells. These properties may be responsible for its anti-atherosclerotic effects in peripheral arterial occlusive disease and lasix!
Other specialists consulted Obstetrics Dr M Hepburn Infectious Diseases Dr R Hague Pharmacy Mrs. F Anderson Infectious Diseases, St. Mary's NHS Trust Dr H Lyall Document Name GG&C HIV Neonates Start Review Dates Start Date 11th October 2006 Review Date 11th October 2008.
We would also like to thank the following individuals for their expert contribution to the Joint Fact-Finding: John Ahearne, Ph.D. Director, Ethics Program Sigma Xi Center James K. Asselstine, J.D. Managing Director Lehman Brothers Inc. Robert J. Budnitz, Ph.D. Group Leader for Nuclear and Risk Sciences Lawrence Livermore National Laboratory James C. Bresee, Sc.D., J.D. Senior Technology Specialist U.S. Department of Energy Martin J. Coveney Vice President, Business Operations Exelon Harold Feiveson, Ph.D. Senior Research Policy Scientist Princeton University Steve Gehl, Ph.D. Director of Strategic Technology Electric Power Research Institute Michael W. Golay, Ph.D. Professor, Nuclear Science and Engineering Massachusetts Institute of Technology Alan Hanson, Ph.D. Executive Vice President AREVA Scott Hempling Director National Regulatory Research Institute Revis James Director, Energy Technology Assessment Center Electric Power Research Institute Paul L. Joskow, Ph.D. Director, Center for Energy and Environmental Policy Research, MIT Richard K. Lester, Ph.D. Professor of Nuclear Science and Engineering Massachusetts Institute of Technology Arjun Makhijani, Ph.D. President Institute for Energy and Environmental Research Per F. Peterson, Ph.D. Department of Nuclear Engineering University of California, Berkeley Michael J. Wallace President Constellation Energy Generation Group and levitra.
AWARD Merit URL : cms.hhs.gov ENTRY TITLE Centers for Medicare & Medicaid Services CMS.hhs.gov website CLASS Miscellaneous Professional CATEGORY Web Site DIVISION Government AUDIENCE Miscellaneous Professionals.
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November 2005 Introduction In December 2000 the Committee on Safety of Medicines CSM ; advised that the use of thioridazine be restricted. This was in response to accumulating data that thioridazine causes dose-related QTc interval prolongation that predisposes to potentially fatal Torsades de Pointes. In July 2005 the MHRA withdrew the UK license for thioridazine following the voluntary withdrawal of the branded Melleril product from the world market. Shared Care As outlined in the NHS circular 1992 Gen 11 ; a consultant may seek the GPs involvement in prescribing for a patient where there is a shared care agreement. This leaflet provides information on thioridazine treatment guidelines for the shared commitment between the consultant and GP concerned. It is anticipated that the GP will be responsible for prescribing when the dose of medication is predictable. Indication for Therapy Thioridazine is indicated for second line treatment of schizophrenia only. It should be reserved for continuation therapy in patients who have been unable to withdraw from thioridazine on previous attempts. It may also be considered for recommencement in patients where this has been found to be a successful treatment in the past, and when no other LJF antipsychotic is effective or tolerated. However, prescribing of thioridazine for new patients will be by specialists only. Preparations and Availability Thioridazine 25mg, 50mg, and 100mg tablets Pack sizes 100 tablets Thioridazine is no longer licensed in the UK but can be imported on an unlicensed basis via IDIS World Medicines Ltd, Millbank House, 171-185 Ewell Road, Surbiton, Surrey KT6 6AX. Telephone 020 8410 0710 Product available: Thioridazin Neuraxpharma ; , manufactured by Neuraxpharm, Germany Recommended Dosage and Administration 150-300mg daily initially in divided doses ; , maximum 600mg daily Cost Average monthly cost per patient, based on a dose of 300mg daily, is 30.16.
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For a decade, we have been witnessing the consolidation of healthcare delivery systems, with hospitals merging facilities or specific specialty services to reduce the overhead cost needed for a designated community or region. Trauma care and interventional cardiology are only two of the specialty services that have been affected, therefore becoming concentrated in large regional facilities. One force behind this change has been the increasing cost of maintaining the technical skills standards and equipment required to provide state-of-the-art care. Only large regional facilities can afford to purchase and maintain such equipment and to attract the staff and physicians needed to provide this specialized care. This has always left rural areas in the lurch. However, the disparity over the years has continued to increase. I have long believed that if a rural town could have only one physician, it should be a specialist in emergency medicine. Stabilization of emergency conditions prior to transport to definitive care is one of the things we do best. As transport times increase due to regionalization and the closure of EDs, initial stabilization becomes even more important. The question then becomes, "How do we get specialists in emergency medicine to practice in rural areas?" This has become of personal interest to me, as I leaving a regional referral center to practice in a small rural hospital during this summer. For me, it was a lifestyle decision. I was once a wilderness ranger for the Forest Service in Oregon, and have always preferred the woods to the city. Most emergency physicians, even those from rural areas, prefer to practice in metropolitan areas. It is easy to see why: higher reimbursement, better clinical support in terms of equipment, support staff and on-call back-up, and more developed levels of.
Pharmalink newsletter May 2007 Polypharmacy is another cause for irrational medicine use. I wish to illustrate this point with my daughter's treatment. When she was younger, I would consult a child specialist for cold and viral fever. On one occasion the prescription for viral fever with running nose contained seven medicines! These were erythromycin tablet 250 mg, paracetamol tablet 250 mg, 1 bottle of cough syrup, ambroxol tablet, cetirizine tablet, Promethazine tablet 10 mg and albendazole tablet. On another occasion a specialist prescribed eight medicines: cetirizine, calamine lotion, paracetamol, erythromycin, antacid digene brand ; , albendazole, promethazine and vitamin C for my daughter's suspected urticaria! In these two examples, the doctors had most probably been offered hefty rewards as incentives to prescribe the medicines by pharmaceutical sales representatives. Another example is about a month ago, I told an eye specialist that gatifloxacin has been withdrawn from the western market when he prescribed gatifloxacin drop for my pink eye condition. In spite of my argument, he advocated for the gatifloxacin drop which is four times costlier than common antibiotic drop and also prescribed a recently marketed antihistaminic which is three and half times costlier than cetirizine.
With use of the Internet increasing among patients and health professionals, there is a wealth of information available aimed at patients. PILs for many prescription and OTC medicines may be downloaded from the electric Medicines Compendium website, : emc.medicines . Type the generic or brand name you require in the search box. A directory of patient leaflets is available from patient pils . The leaflets are listed by disease or symptom category, and have been validated by Prodigy. Great Ormond Street Hospital has produced over 300 factsheets for patients and parents, available at ich.ucl.ac factsheets index . Specialist areas such as cancer chemotherapy and HIV are covered, and are regularly updated. Many self-help and support groups produce leaflets for patients. These may be of variable quality but can provide a useful summary of a disease or treatment. A directory of over 800 UK self-help groups is available at ukselfhelp.
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4. DURATION OF TREATMENT Advice will be given to the GP by the secondary care Specialist on duration of treatment and dose changes for each individual patient. Where patients are continuing treatment with atomoxetine beyond 1 year, reevaluation of the need for therapy by a specialist in the treatment of ADHD is recommended. 5. ADVERSE EFFECTS The following have been reported: Upper abdominal pain Decreased appetite Short term weight loss and long term weight gain Somnolence Nausea Vomiting Fatigue Hypotension Headache and dizziness Dyspepsia Constipation Flu like symptoms Early morning wakening, irritability and mood swings Suicide related events, aggression, hostility and emotional lability Seizures Cardiac effects including rare QT interval prolongation Rare reports of hepatotoxicity Priapism Raynaud's syndrome Further adverse effects have also been reported, please seek further information and danazol.
Indication: SEVERE PSORIASIS General Guidance This protocol sets out details for the shared care of patients taking ciclosporin and should be read in conjunction with the General Guidelines for Shared Care. Sharing of care requires communication between the specialist, GP and patient. The intention to share care should be explained to the patient by the doctor initiating treatment. The doctor who prescribes the medication legally assumes keep themselves informed about the medicines they prescribe, their appropriateness, effectiveness and cost. They should also keep up to date with the relevant guidance on the use of the medicines and on the management of the patient's condition. Background Ciclosporin is a potent immunosuppressive agent that has been shown to have marked beneficial effects in patients with severe psoriasis. Oral ciclosporin is indicated for patients with severe psoriais in whom conventional therapy is ineffective or inappropriate. Responsibilities A. Consultant responsibilities 1. Baseline and continued monitoring of biochemical, haematological and clinical parameters see page 2 ; 2. Initiate therapy following full discussion with the patient of benefits and risks 3. Titrate ciclosporin dose adjusting dose as appropriate and undertake monitoring of clinical response and side effects. 4. When treatment is stabilised, send shared care agreement request to GP. 5. Respond to any request from GP to review the patient due to adverse effects of therapy. 6. Advise the GP on continuing or stopping ciclosporin therapy following medical review of the patient and associated drug therapy 7. Notify GP if patient is failing to attend for appropriate monitoring and advise GP on appropriate action.
RIGHT 6 Right to be Fully Informed 1 ; Every consumer has the right to the information that a reasonable consumer, in that consumer's circumstances, would expect to receive, including . b ; An explanation of the options available, including an assessment of the expected risks, side effects, benefits, and costs of each option . RIGHT 7 Right to Make an Informed Choice and Give Informed Consent 1 ; Services may be provided to a consumer only if that consumer makes an informed choice and gives informed consent, except where any enactment, or the common law, or any other provision of this Code provides otherwise 6 ; Where informed consent to a health care procedure is required, it must be in writing if . d ; There is a significant risk of adverse effects on the consumer.
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Is ADHD Inherited? We now know that ADHD is very much a "family affair". At the present time, specialists agree that at least 30% to 40% of children diagnosed with ADHD have relatives with the same type of problem. However, this doesn't mean that all children in a family will have ADHD. In most families with ADHD, there is usually only one child who shows these signs and symptoms. How Common Is Attention-Deficit Hyperactivity Disorder? Attention-deficit hyperactivity disorder is found in as many as 1 in every 20 children. Studies have shown that boys with attention-deficit hyperactivity disorder outnumber girl with the disorder about three to one. Children and adolescents with attentiondeficit hyperactivity disorder are at risk for many other disorders. About half of all young people with attention-deficit hyperactivity disorder also have oppositional or conduct disorder, and about a fourth have an anxiety disorder. As many as one-third have depression, and about one-fifth have a learning disability. Sometimes a child or adolescent will have two or more of these disorders in addition to attentiondeficit hyperactivity disorder. Also, children with attention-deficit hyperactivity disorder are at risk for developing personality disorders and substance abuse disorders when they are adolescents or adults. Attention-deficit hyperactivity disorder is a major reason why children are referred for mental health care. Boys are more likely to be referred for treatment than girl, in part because many boys with attention-deficit hyperactivity disorder also have conduct disorder. The mental health services and special education required by children and adolescents with attention-deficit hyperactivity disorder cost millions of dollars each year. Underachievement and lost productivity can cost these young people and their families even more. How is the diagnosis made? Diagnosis is not a simple matter, and may require more than one specialist. It's a mistake for a "snap" diagnosis to be made or to try to intervene before all of the facts are known. Evaluation should be done by pediatricians and or neurologists with a background in behavioral and developmental problems, licensed mental health professionals, speciallytrained family and general practitioners, or by a team of professionals from the all of these specialties. It is important for the diagnosis: To explore all of the possibilities that could explain the child's behaviors. To find if there are any additional problems such as learning disabilities, conduct disorders, depression, anxiety, or various physical illnesses.
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Nicholas J Talley is professor of medicine, Nghi Phung is a gastroenterologist, and Jamshid S Kalantar is a staff specialist in gastroenterology, department of medicine, University of Sydney, Nepean Hospital, Penrith, New South Wales, Australia. The ABC of the upper gastrointestinal tract is edited by Robert Logan, senior lecturer in the division of gastroenterology, University Hospital, Nottingham; Adam Harris, consultant physician and gastroenterologist, Kent and Sussex Hospital, Tunbridge Wells; J J Misiewicz, honorary consultant physician and joint director of the department of gastroenterology and nutrition, Central Middlesex Hospital, London; and J H Baron, honorary professorial lecturer at Mount Sinai School of Medicine, New York, USA, and former consultant gastroenterologist at St Mary's Hospital, London.
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