Manejo del Dolor por Cncer Elliott K, Foley KM. Neurologic pain syndromes in patients with cancer. Neurol Clin 1989; 7 2 ; : 333-60. Ellison NM. Opioid analgesics: Toxicity and their treatments. In: Patt RB, editor. Cancer pain. Philadelphia: JB Lippincott Co.; 1993. p.185-94. Elomaa I, Blomqvist C, Grohn P, Porkka L, Kairento AL, Selander K, Lamberg-Allardt C, Holmstrom T. Long-term controlled trial with diphosphonate in patients with osteolytic bone metastases. Lancet 1983; 1 8317 ; : 146-9. Enddicott J. Measurement of depression in patients with cancer. Cancer 1984; 53 10 suppl. ; : 2243-9. Epstein JB. Infection prevention in bone marrow transplantation and radiation patients. NCI Monogr 1990; 9: 73-85. Espinoza LR, Aguilar JL, Berman A, Gutierrez F, Vascy FB, Germain BF. Rheumatic manifestations associated with human inmunodeficiency virus infection. Arthritis Rheuman 1989; 32 12 ; : 1615-22. Estes D, Kaplan K. Lack of platelet effect with the aspirin analog, salsalate. Arthritis Rheuman 1980; 23 11 ; : 1303-7. Evans PJ, Lloyd JW, Jack TM. Cryoanalgesia for intractable perineal pain. J R Soc Med 1981; 74 11 ; : 804-9. Facing forward: A guide for cancer survivors. US Department of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, July 1990. NIH Pub. No. 90-2424, P.43. Fainsinger R, Bruera E. Treatment of delirium in a terminally ill patient. J Pain Symptom Manage 1992; 7 1 ; : 54-6. Fairchild VM, Salerno LM, Wedding SL, Weinberg E. Physical therapy. In: Raj PP, editor. Practical management of pain: with special emphasis on physiology of pain syndromes and techniques of management. Chicago: Yearbook Medical Publishers; 1986. p.839-52. Fawzy FI, Cousins N, Fawzy NW, Kemey ME, Elashoff R, Morton D. A structured psychiatric intervention for cancer patients. I. Changes over time in methods of coping and effective disturbance . Arch Gen Psychiatry 1990; 47 8 ; : 720-5. Ferrante FM, Ostheimer GW, Covino BG, editors. Patient-controlled analgesia. Boston: Blackwell Scientific Publications; 1990. Ferrell BA. Assessment and management of pain in nursing homes. Ann Intern Med, in press for Annals of Internal Med. 1994 ; . Ferrell BA. Pain management in elderly people. J Geriatr Soc 1991; 39 1 ; : 64-73. Ferrell BA, Ferrell BR, Osterwiel D. Pain in the nursing home. J Geriatr Soc 1990; 38 4 ; : 409-14.
W.J. Alonso1, C. Viboud 2, L. Simonsen3, E.H. Hirano4, L.Z. Daufenbach5, M.A. Miller2. 1Origem Scientific Consultancy, Florianpolis, Brazil; 2Fogarty International Center, National Institutes of Health, Bethesda, MD, USA; 3National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA; 4 Mechanical Engineering Department, UFSC, Florianpolis, Brazil; 5 Secretariat of Health Surveillance, Ministry of Health, Brasilia, Brazil Influenza has marked seasonal patterns in wintertime in temperate regions of the world and much less defined seasonality in tropical and sub-tropical zones. Although influenza circulates globally, the transition in seasonality has not been described along a wide range of latitudes. Here we investigate influenza seasonal patterns in the geographically diverse Brazilian territory, using mortality and laboratory surveillance data. Monthly mortality rates for pneumonia and influenza P&I ; were obtained from 1979 to 2001 for each of the 27 Brazilian states. De-trended time series were analyzed by Fourier decomposition to capture the amplitude and timing of annual and bi-annual epidemic cycles. The resulting seasonal parameters were compared across the latitudes of the state capitals, ranging from equator + 5oN ; to subtropics -35oS ; . Virus surveillance data from recent years provided independent confirmation of the results. Overall in Brazil, the major annual ; seasonal peak of influenza mortality occurs in June-July winter ; , with a second peak of lesser amplitude 6 months apart. The major component was most intense in southernmost states, gradually attenuating towards center states 15oS ; p 0.001 ; , and regaining intensity towards the North p 0.013 ; . The timing of annual peaks was also influenced by latitude, gradually ranging from early April autumn ; to late July winter ; along a North-South axis. These patterns correlated with the timing of influenza viral isolations. Our study indicates that influenza travels southwards across Brazil in ~3 months, originating from equatorial and low population regions and moving towards temperate and highly populous regions. This suggests that environmental or geographical factors play a more important role in driving the seasonal patterns of influenza in Brazil than population factors, for example, .
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Table 4. Conventional and Molecular Cytogenetics 42 47 ; Level 1: 25 mg po daily + G-CSF Level 2: 15 mg po daily Level 3: 10 mg po daily Level 2: 15 mg po daily Level 3: 10 mg po daily Level 2: 15 mg po daily Level 3: 10 mg po daily Level 1: 20 mg orally on days 1, 8, 15 and 22 Level 2: 20 mg orally on days 1 and 15 Reduction to 250 mg twice daily per tolerance Conventional Abnormal Multiple Single Molecular Abnormal numeric and structural ; FGFR3-IGH gene rearrangements BCL1-IGH gene rearrangements del 13q14 Trisomy 11 Tetrasomy 11 29 42 Patients.
Weanling albino rats, of the Sprague-Dawley strain, weigh ing 40 to 50 gm, were used in these experiments. The compo sition of the basal ration used throughout was : casein, 9% ; DL-threonine, 0.5%; L-histidine, 0.2%; DL-methionine, 0.5%; corn oil, 5% ; salts XIV, 4% ; vitamins, in milligrams per 100 gm of diet, as follows : thiamine hydrochloride 0.5, riboflavin 1.0, niacin 1.0, pyridoxine 0.5, calcium pantothenate 2.5, biotin 0.02, p-aminobenzoic acid 30, i-inositol 100, folie acid 0.02, choline chloride 200, vitamin B!2 0.002, Menadione 0.5. Sucrose was added to make 100%. When supplemented, antibiotics were given at a level of 0.01% of the diet. DL-Tryptophan was fed at a level of 0.2% at the expense of the sucrose. The rats were given two drops of oleum-percomorphum, directly into the mouth, weekly, and were housed in screen-bottom indi vidual cages. At least minimal levels of amino acids were added to the 9% casein basal diet to conform to the amounts recommended by Rose '37 ; . All rats were weighed twice weekly and fed their experimental diets for three weeks. RESULTS The data are presented in tables 1 and 2. It was found re peatedly that terramycin, achromycin, and erythromycin, in cluded at a level of 0.01% of the diet, were able to effect a significant increase in growth of male rats, an average of 7 gm per week over that obtained with the 9% casein diet supple mented with amino acids. Chloromycetin, dihydrostreptomycin, bacitracin, polymyxin were without effect on the growth of male rats, while penicillin was borderline. Terramycin, achromycin and erythromycin were tested with female rats. There seems to be a slight growth increase in and acomplia.
21.03.2007 24.03.2005 2006.01 ; A61K 38 18 2006.01 ; A61P 19 08 10.09.2004 Wyeth, Madison, New Jersey 07940, US ETEX CORPORATION, Cambridge, MA 02139, US LI, Rebecca, Bedford, MA 01730, US SEEHERMAN, Howard, Cambridge, MA 02138, US KIM, Hyun, Bedford, MA 01730, US Kalciumfosftov pevn tycinky pro injekcn aplikaci osteogennch protein 12.09.2003 502493 P US PCT US2004 029560 WO 2005 025595 Spolecn advoktn kancel Vsetecka Zelen Svorck Kalensk a partnei, JUDr. Milos Vsetecka, Hlkova 2, Praha 2, 12000 EP 1684920 21.03.2007 02.06.2005 ; B08B 1 00 2006.01 ; B08B 3 08 2006.01 ; B08B 1 04 19.10.2004 ThyssenKrupp Drauz Nothelfer GmbH, 74076 Heilbronn, DE SCHNEIDER, Johannes, 54340 Bekond, DE Zpsob cistn lemovacch kladek umstnch na robotickm rameni a cistic stanice k provdn tohoto zpsobu 17.11.2003 10353742 DE PCT EP2004 011795 WO 2005 049236 KANIA, SEDLK, SMOLA Patentov a znmkov kancel, Ing. Ji Malsek, Mendlovo nm. 1a, Brno, 60300 EP 1694318 14.03.2007 30.06.2005 ; A61K 31 135 2006.01 ; A61P 25 00 2006.01 ; A61P 43 00 13.12.2004 04803781.6 SCHWARZ PHARMA AG, 40789 Monheim Rhld., DE SCHELLER, Dieter, 41470 Neuss, DE HANSEN, Klaus, 41516 Grevenbroich-Mnchrath, DE S ; jako D3 agonistick terapeutikum 18.12.2003 10359528 DE PCT EP2004 014143 WO 2005 058296 Cermk Hoejs Myslil a spol., JUDr. Karel Cermk, advokt, Nrodn 32, Praha 1, 11000 EP 1696940 21.03.2007 30.06.2005 A61K 35 16 A61P 7 02 20.12.2004.
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Days, respectively, after stopping the carcinogen ; and rats fed both high vitamin A and amygdalin survived significantly longer 128 days ; . 4 rats in these groups which died early were cannibalized, but all of the rest were either dead or moribund with huge liver tumors when the experiment was terminated 7 months after stopping the carcinogen treatment, with the exception of 1 rat on the amygdalin diet which had only small cancers and would have lived probably another month. The fetalism of malignant tumors must be explained by any potentially valid theory of the fundamental nature of the malignant process. The currently popular mutation theory is inadequate for this reason. These results suggest the usefulness of both vitamin A and amygdalin in modulating rat liver carcinogenesis in the study of tumor fetalism and other promotion-specific events". " Since that time, Laetrile and other Betaisothiocyanates which are commonly found in cruciferous vegetables have been acknowledged to be of great value in the prevention of cancer by the National Research Council as well as the American Cancer Society. As early as 40-50 years ago, scientists felt that measures which supported mitochondrial function, the production of ATP were crucial in the treatment of cancer. It appears that laetrile may do this by acting as a highly efficient antioxidant. The cancer therapies listed in these three books must of course, undergo similar penetrating analysis before being incorporated into an integrated cancer treatment program designed to cure cancer. The metabolic typing and dietary adjustments based on such typing are discussed in Moss's book in conjunction with Nicholas Gonzales' approach. This originated as an integral part of the highly successful cancer therapies of William Donald Kelley. Nicholas J. Gonzales, M.D., became interested in Kelley's method while a student at Cornell University Medical College in the late 1970's. After graduating, Dr. Gonzales did postgraduate work with Robert A. Good, M.D., Ph.D., then president of Sloan-Kettering Institute, and thoroughly investigated Kelley's treatments. In a lengthy unpublished monograph, One Man Alone and acyclovir.
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2 the dosage formulation of claim 28, wherein the ratio of said auxiliary to said gelatin, collagen hydrolyzate or mixture ranges from 5: 1 to 500: 3 the dosage formulation of claim 29, wherein said weight ratio ranges from 5: 1 to 30: 3 the dosage formulation of claim 1 which is suitable for pharmaceutical administration.
The Danish outdoor furniture manufacturer, ScanCom, exports highquality, certified timber from Brazil to its production facilities around the world supporting the Brazilian economy while helping protect the environment. Established in 1995, ScanCom International A S is one of the world's largest manufacturers of outdoor furniture. With its corporate head office in Denmark, ScanCom has production operations in Vietnam, Indonesia and Brazil. The company's products are sold in over 10, 000 retail outlets throughout the world.
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Pain Medication A new policy identifies appropriate utilization of narcotic analgesics. Quantity limits will apply to select pain medications. Blood Modifiers--RBC Agents A new policy requires pre-authorization for Epogen, Procrit and Aranesp. Tyrosine Kinase Inhibitors Tarceva was added to the policy and requires pre-authorization. Iressa also requires pre-authorization.
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